Name: Dr. Lin Han
Institution: Northwest A&F University
Address: 28# Xinong Road, Yangling, Shaanxi, China
Phone: 0086-029-58102522
Email: hanlin2019@nwafu.edu.cn
Profile
Dr. Lin Han is an associate professor with extensive experience in molecular nutrition and health food research. He is currently working at College of Food Science and Engineering, Northwest A&F University, Shaanxi, China, investigating molecular mechanisms of the active substances, including polyphenols and flavonoids, to prevent and improve chronic diseases, especially obesity-related diseases, such as non-alcoholic fatty liver disease (NAFLD), diabetes and cardiovascular disease (CVD). The extensive project utilizes multi-omics techniques, including metagenomics, transcriptomics, proteomics, and metabolomics to analyze samples from animal and cell culture models that treated with or without active substances. Dr. Han is a member of Chinese Society of Nutrition and a Guest Editor of Nutrients (IF 6.706, 2022). He has published more than 30 peer-reviewed articles (first or corresponding author), including 11 SCI and EI papers with h-index of 14 and 679 total citations (2022).
Experience history
Associate professor 2019– Now
College of Food Science and Engineering, Northwest A&F University, Shaanxi, China
Lecturer 2010– 2015
Chongqing Three Gorges University
Education
Ph. D of Food Science 2015-2019
Northwest A&F University, Shaanxi, China
Masters of Food Science 2007-2010 Hainan University, Hainan, China
Bachelor of Food Science and Engineering 2003-2007
Hainan University, Hainan, China
Part of publications
Yao Xiao, Kailin Li, Ji Bian,…, Lin Han#, Lan Gong#, Min Wang#.Urolithin A attenuates diabetes-associated cognitive impairment by amelioratingintestinal barrier dysfunction via N-glycan biosynthesis pathway. Molecular Nutrition & Food Research, 2022, 2100863(# corresponding author). (IF2021="6.575," JCR Q1)
Qiong Yang, Yao Zhang, Luqi Li,…, Lin Han#, Min Wang#. D-chiro-Inositol facilitates adiponection biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition. Food & Function, 2022, 13, 7192-7203 (# corresponding author). (IF2021=6.317, JCR Q1)
Lin Han, Yao Zhang, Jia Li, et al. Phloretin attenuation of hepatic steatosis via an improvement of mitochondrial dysfunction by activating AMPK-dependent signaling pathways in C57BL/6J mice and HepG2 cells. Food & Function, 2021, 12, 12421-12433. (IF2021=6.317, JCR Q1)
Lin Han, Jie Li, Jia Li, et al. Activation of AMPK/Sirt3 pathway by phloretin reduces mitochondrial ROS in vascular endothelium by increasing the activity of MnSOD via deacetylation. Food & Function. 2020, 11, 3073-3083. (IF2021=6.317, JCR Q1)
Lin Han, Qing Yang, Jia Li, et al. Protocatechuic acid ameliorates endothelial oxidative stress through regulating acetylation level via CD36/AMPK pathway. Journal of Agricultural and Food Chemistry. 2019, 67, 7060-7072. (IF2021=5.895, JCR Q1)
Lin Han, Qing Yang, Wenfang Ma, et al. Protocatechuic acid ameliorated palmitic acid induced oxidative damage in endothelial cells through activating endogenous antioxidant enzymes via an adenosine-monophosphate-activated-protein-kinase-dependent pathway. Journal of Agricultural and Food Chemistry. 2018, 40, 10400-10409. (IF2021=5.895, JCR Q1)
Lin Han, Lingling Zhang, Wenfang Ma, et al. Proanthocyanidin B2 attenuates postprandial blood glucose and its inhibitory effect on alpha-glucosidase: analysis by kinetics, fluorescence spectroscopy, atomic force microscopy and molecular docking. Food & Function. 2018, 9, 4673-4682. (IF2021=6.317, JCR Q1)
Lin Han, Chun Fang, Ruixue Zhu, et al. Inhibitory effect of phloretin on α-glucosidase: kinetics, interaction mechanism and molecular docking. International Journal of Biological Macromolecules. 2017, 95, 520-527. (IF2021=8.025, JCR Q1)
Lingling Zhang*, Lin Han*, Shiyi Yang, et al. The mechanism of interactions between flavan-3-ols against α-glucosidase and their in vivo antihyperglycemic effects. Bioorganic Chemistry, 2019, 85, 364-372 (* co-first author). (IF2021="5.307," JCR Q2)
