Gao Jinming

Sourse:   Date:2019-01-17

  Brief Introduction of Gao Jinming

  Gao Jinming

  PhD, Professor, Dean

  1.EDUCATION

  2001, Ph.D., Phytochemistry Key Lab., Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China

  1998, M.S., Department of Applied Chemistry, Northwest A& FUniversity,Yangling, China

  1986, B.S.,Department of Chemistry, Shaanxi Normal University, Xi’an, China 

  2.SCIENTIFI RESEARCH

  In recent years, Dr. Gao is being responsible for several ongoing projects, including two the National Natural Science Foundation of China (NSFC), the sub-project of National Key R&D Program ofChina. Up to now, he has published over 180 SCI scientific papers (such asChem. Rev.、J. Am. Chem. Soc.、Nat. Prod. Rep.、Org. Lett.) including review articles, ten patents. Currently, his research interests include natural products chemistry as well as structure–activity relationships in pharmacology.

  3.RESEARCH INTERESTS

   Natural Products Chemistry;

   SARs and synthesis of bioactive natural products;

   Biosynthesis and regulation of Natural Products of importance.

  4. PUBLICATIONS SELECTED

  (1) Yu-Bin Bai, ZaigangLuo, Yuguang Wang, Jin-Ming Gao*, Liming Zhang*. Au-Catalyzed Intermolecular [2+2] Cycloadditions between Chloroalkynes and Unactivated Alkenes. Journal of the American Chemical Society, 2018, 140: 5860–5865.

  (2) Ding Li#,Thi-Mai-Luong Tuong#, Wen-Jia Dan, Yanliang Ren*, Xuan-Nien Hoang, An-Ling Zhang, Jin-Ming Gao*. Synthesis and biological evaluation of isobutyrophenone analogs as potential inhibitors of class-II fructose-1,6-bisphosphate aldolase. Bioorganic & Medicinal Chemistry,2018, 26(2)386-393.

  (3) Dan Tang#,  Ling-Li Liu#,Qiu-Rui He, Wen Yan, Ding Li, Jin-Ming Gao*.Ansamycins with potential anti-proliferative and anti-neuroinflammatory activity from the moss soil-derived Streptomyces cacaoisubsp. asoensis H2S5. Journal of Natural Products,2018,81(9), 1984–1991.

  (4) Chen-Yu Cao, Cheng-Chen Zhang, Xin-Wei Shi, Ding Li, Wei Cao, Xia Yin, Jin-Ming Gao*, Sarcodonin G derivatives exhibit distinctive effects on neurite outgrowth by modulating NGF signaling in PC12 Cells, ACS Chemical Neuroscience, 2018,9: 1607–1615.

  (5) Jing Wei#, Yuanyuan Cheng#, Wan-Hui Guo, Da-Cheng Wang, Qiang Zhang, Ding Li, Jianhui Rong*, Jin-Ming Gao*. Molecular diversity and potential anti-neuroinflammatory activities of cyathane diterpenoids from the Basidiomycete Cyathus africanus. Scientific Reports, 2017, 7: 8883. 

  (6) Qiang Zhang#, Hao-Yu Tang#, Min Chen,Jie Yu, Hui Li, Jin-Ming Gao*. Natural products driven diversity via skeletal remodeling of caryophyllene β-lactam. Organic & Biomolecular Chemistry, 2017, 15(20):4456-4463.

  (7) Xin Yu, Jiadong Hu, Zhigao Shen, Hui Zhang, Jin-Ming Gao, Weiqing Xie*. Stereospecific construction of contiguous quaternary all-carbon centers by oxidative ring contraction. Angew. Chem. Int. Ed.2017, 56(1): 350–353.

  (8) Shuai Dong, Kiran Indukuri, Derrick L. J. Clive*, Jin-Ming Gao*. Models of the BC ring systems of MPC1001 and MPC1001F. Chemical Communications.2016, 52, 8271-8274.

  (9) Bo Luo, Jin-Ming Gao*, Mark Lautens*. Palladium-catalyzed norbornene-mediated tandem amination/cyanation reaction: a new method for the convergent synthesis of ortho-aminated benzonitriles. Organic Letters, 2016, 18, 4166−4169.

  (10) Bai, Rui; Zhang, Cheng-Chen; Yin, Xia; Wei, Jing; Gao, Jin-Ming*. Cyathane diterpenoids with neurotrophic activity from cultures of the fungus Cyathus striatus. Journal of Natural Products, 2015, 78(4):783–788.

  (11) Bai, Meng-Meng#; Shi, Wei#; Tian, Jun-Mian; Lei Ming; Kim, Young Ho; Kim, Jang Hoon*; Sun, Ya Nan; Gao, Jin-Ming*. Soluble epoxide hydrolase inhibitory and anti-inflammatory components from the leaves of Eucommia ulmoides Oliver (Duzhong). Journal of Agricultural and Food Chemistry,2015, 63(8): 2198–2205.

  (12) Zhang, Qiang; Xiao, Jian; Sun, Qing-Qing; Qin, Jian-Chun; Pescitelli, Gennaro; Gao, Jin-Ming*. Characterization of cytochalasins from the endophytic Xylaria sp. and their biological functions. Journal of Agricultural and Food Chemistry, 2014, 62(45): 10962–10969.

  (13) Dong-Mei Wang#, Cheng-Chen Zhang#, Qiang  Zhang, Nusrat Shafiq,Gennaro Pescitelli, Deng-Wu Li, Jin-Ming Gao*. Wightianines A–E, dihydro-β-agarofuran sesquiterpenes from Parnassia wightiana, and their antifungal and insecticidal activities. Journal of Agricultural and Food Chemistry, 2014, 62(28): 6669–6676.

  (14) Shuai Dong, Jiang-Jiang Tang*, Cheng-Chen Zhang, Jun-Mian Tian, Jun-Tao Guo, Qiang Zhang, He Li, Jin-Ming Gao*.Semisynthesis and in vitro cytotoxic evaluation of new analogues of 1-O-acetylbritannilactone, a sesquiterpene from Inula britannica. European Journal of Medcinal Chemistry2014, 80, 71–82.

  (15) Qiang Zhang, Shi-Qiong Wang, Hao-Yu Tang, Xiao-Jun Li, Lu Zhang, Jian Xiao, Yu-Qi Gao, An-Ling Zhang,Jin-Ming Gao*. Potential allelopathic indole diketopiperazines produced by the plant endophytic Aspergillus fumigatususing the one strain−many compounds method. Journal of Agricultural and Food Chemistry, 2013, 61(47):11447–11452.

  (16) Jin-Ming Gao*, Sheng-Xiang Yang, Jian-Chun Qin. Azaphilonoids: Chemistry and Biology, Chemical Reviews, 2013, 113(7): 4755–4811. (IF = 45.661)

  (17) Yu-Bin Bai, An-Ling Zhang, Jiang-Jiang Tang, Jin-Ming Gao*. Synthesis and antifungal activity of 2-¬chloromethyl-1H-¬benzimidazole derivatives against phytopathogenic Fungi in vitro. Journal of Agricultural and Food Chemistry, 2013, 61 (11): 2789–2795. 

  (18) Han-Wei Liu, Xiu-Zhu Yu, Daniele Padula, Gennaro Pescitelli, Zhi-Wei Lin, Fei Wang, Kai Ding, Ming Lei, Jin-Ming Gao*. Lignans from Schisandra sphenathera Rehd. et Wils. and synthetic schisantherin A analogues: absolute configuration, and their estrogenic and anti-proliferative activity.European Journal of Medcinal Chemistry, 2013, 59(1): 265-273.

  (19) Xiao-Jun Li, Qiang Zhang, An-Ling Zhang, Jin-Ming Gao*.Metabolites from Aspergillus fumigatus, an endophytic fungusassociated with Melia azedarach, and their antifungal, antifeedant, and toxic activities. Journal of Agricultural and Food Chemistry, 2012, 60 (13): 3424–3431.(ESI highly cited paper)

  (20) Sheng-Xiang Yang, Hong-Peng Wang, Jin-Ming Gao*, Qiang Zhang, Hartmut Laatsch*, and Yi Kuang. Fusaroside, a uinque glycolipid isolated from Fusarium sp., an endophytic fungus in Melia azedarach. Organic & Biomolecular Chemistry, 2012, 10(4): 819-824. 

  (21) Jin-Ming Gao*,Wen-Jun Wu, Ji-Wen Zhang, Yasuo Konishi, The dihydro--agarofuran sesquiterpenoids, Natural Product Reports, 2007, 24(5): 1153–1189. (IF = 11.715)

  5.CONTACT

  College of Chemistry and Pharmacy

  Northwest Agriculture & Forestry University

  22 Xinong Road, Yangling, Shaanxi 712100, CHINA

  Telephone:(86) 29-87092335; 

  Fax: (86) 29-87092226

  Email: jinminggao@nwsuaf.edu.cn