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Notice of Academic Report“Complex Natural Product as a Driving Force for Discoveries in Organic Synthesis, Chemical Biology, and Drug Development”

Sourse:   Date:2018-05-11

Tiltle:Complex Natural Product as a Driving Force for Discoveries in Organic Synthesis, Chemical Biology, and Drug Development

Speaker: XIiao Gang Lei  professor of  Beijing University

Time:   3:30 PM– 5:00 PM on May .14  2018(monday)

Venue:A210  meeting room  of food- Building

Summary of the report:

Complex natural products provide tremendous opportunities to shape the landscape of organic synthesis, as well as to impact the biomedical research and drug discovery. My laboratory conducts research at the interface between chemistry and biology. We systematically use bioactive small molecules, particularly natural products, to study their biological functions, elucidate molecular mechanisms of the important biological pathways, and develop novel therapeutic agents for currently intractable diseases. Herein, I would like to disclose our recent endeavors towards the biomimetic syntheses of a number of structurally complex and bioactive natural products as well as using the natural product-based chemical probes to dissect programmed cell death and develop anticancer and anti-inflammation drug candidates.